BOSTON (WHDH) - Two Boston firefighters were hospitalized after crews descended a high-rise in Government Center for the second time in as many months after a fire broke out Saturday.

According to Boston Fire, flames at 1 Congress Street spread across multiple floors, traveling through duct works and shafts. A fourth alarm was ordered shortly before 1:00 p.m.

“Upon arrival, (crews) found fire in the utility shaft that had started in floor six, (and went) as high as floor 25,” said Chief Paul Burke.

Smoke could be seen pouring out the lower side of the building early Saturday afternoon.

At least two firefighters were treated and taken to the hospital for smoke inhalation after crews spent the day traversing dozens of flights of stairs to get at the flames.

“The heat is pretty bad today, with all the gear and the high-rise fire, there’s a lot of exertion, traveling up to the higher floors,” Burke added.

Firefighters previously combated a five-alarm fire at the 43-story building in June.

The building is adjacent to Government Center Parking garage, where a deteriorated support column caused disruptions in to Green and Orange Line service in the area.

In both cases, construction crew workers on-site were able to safely evacuate.

The cause of the fire remains under investigation.

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