A woman suffered serious injuries Tuesday after a motor vehicle crash in Worcester, police say.

Officers responding to a reported motor vehicle accident in the area of 126 May St. about 11:30 p.m. found a guardrail in the middle of the road and a Toyota 4Runner in the roadway that had come to rest on its roof, according to the Worcester Police Department.

When officers arrived on the scene, members of the Worcester Fire Department were already rendering medical aid to a 39-year-old female victim, who was still trapped inside the vehicle.

The female was unconscious as she was removed from the vehicle.

A 43-year-old male occupant was outside the vehicle and appeared to be disoriented and had minor injuries.

Both the male and female were transported to a local hospital for treatment. The male was treated and released.

The female remains hospitalized with undisclosed injuries and listed in serious condition.

A preliminary investigation revealed the 4Runner had turned left onto May Street from Park Avenue and struck a guardrail in front of 126 May St., which caused the vehicle to flip onto its roof.

Police were told a second vehicle may have been involved in the accident but didn’t remain on scene.

The investigation is ongoing.

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