(CNN) — More than 700,000 people die by suicide each year, according to the World Health Organization.

Translated: Every 40 seconds, someone in the world takes their own life. That’s a sobering statistic to ponder today, on 2021’s World Suicide Prevention Day.

Suicide rates have been climbing for years in some parts of the world. In the United States alone, suicide rates have increased by 35% between 1999 and 2018. The US Centers for Disease Control and Prevention calls suicide a “growing public health problem.”

Experts fear suicidal thoughts may escalate due to economic hardship and mental stress caused by another lethal crisis facing the world — Covid-19, the disease caused by the novel coronavirus.

A leading public health group estimated last year that as many as 75,000 Americans could die due to drug or alcohol misuse and suicide connected to the pandemic.

President Joe Biden expressed his concern in a proclamation released Thursday announcing that September 10 is World Suicide Prevention Day in the US.

“In 2019, suicide was the 10th leading cause of death in the United States, and the second leading cause of death for young people between the ages of 10 and 34,” Biden wrote.

“And that was before the COVID-19 pandemic compounded, for many, feelings of isolation, exhaustion, and economic and public health-related anxieties. Increased rates of depression have sparked concern that we will see a further increase in suicide rates.”

study released in June further highlights those fears. The CDC found emergency department visits for suspected suicide attempts started to increase in May 2020 among adolescents ages 12 to 17, especially girls.

“The mean weekly number of these visits was 26.2% higher during summer 2020 and 50.6% higher during winter 2021 compared with the corresponding periods in 2019,” the CDC researchers wrote.

Widespread risk

All ages, races and income levels are at risk, with 77% of all suicides occurring in lower- to middle-income countries, according to WHO. Globally, youth can be hardest hit: Suicide is the fourth leading cause of death in 15- to 19-year-olds around the world, the agency said.

And that’s only part of the grim picture. For each person who has died by suicide, many more people think about or attempt suicide, according to the CDC. In 2019, 12 million American adults seriously thought about suicide, 3.5 million planned a suicide attempt, and 1.4 million attempted suicide.

“If you or a loved one are thinking about suicide, please know that you are not alone and help is available 24/7 by calling the National Suicide Prevention Lifeline at 1-800-273-TALK or through the Crisis Text Line by texting HOME to 741741,” Biden wrote.

“Next July, the new Mental Health Crisis Line 9-8-8 will take effect. By expanding the crisis line and investing in our Nation’s crisis care infrastructure, we have the opportunity to prevent suicides and save lives,” he continued.

There are ways each of us can help prevent suicide. Here’s how to do your part.

Recognize distress signals

There are many risk factors that can lead to an increase in thoughts about taking one’s life. It’s important to recognize these in yourself or a loved one, experts say, because many people do not talk about their thoughts of suicide in advance.

Is there a history? People who have a mood, anxiety, alcohol or other substance use disorder, a major physical illness or a history of trauma, abuse or suicide in their family are at higher risk, according to the CDC.

Was there a loss? A death in the family, the loss of a job or the loss of a relationship is a risk factor for suicidal behavior, especially if they feel isolated or alone without social support, the American Foundation for Suicide Prevention says.

Economic distress is a reality facing millions who are out of work right now due to Covid-19-related job loss, social isolation or quarantine.

Is there a belief system that honors personal sacrifice? People with religious or cultural attitudes that see suicide as a noble resolution of a personal dilemma are at higher risk, according to the Suicide Prevention Lifeline.

Can they get a gun? Research has shown that easy access to firearms is also a key risk factor.

Did the person survive a suicide attempt? Any previous suicide attempt is the single most important risk factor, according to the WHO. But there is also an odd “copycat” phenomena where suicides increase after local clusters of suicide or deaths of famous celebrities reported in the media. For example, deaths by suicide rose by 10% in the US after comedian Robin Williams ended his life in 2014.

Look for actions

Again, not everyone will give their friends and loved ones verbal hints about their suicidal thoughts. That’s why it’s important to look at actions as well as words to recognize warning signs.

According to the National Institute of Mental Health, be wary if your loved one:

  • Increases their use of alcohol or drugs or starts to behave recklessly, such as driving while intoxicated or without a seat belt.
  • Has extreme mood swings, from euphoria to the depths of depression or appears agitated, expresses rage or talks about seeking revenge.
  • Sleeps too much or too little or withdraws or isolates from others.
  • Appears to be in unbearable psychological pain or talks about being hopeless or a burden to friends or family, or talks about feeling trapped or having no reason to live.
  • Begins to search online for ways to kill themselves, such as buying a gun or obtaining medical prescriptions.
  • Begins to give away prized possessions or visits or calls to say goodbye.

Be sure to regularly check on loved ones. During the pandemic families and friends are more isolated and alone and many warning signs may be tough to recognize. Listen carefully when you talk to them about to their concerns and observe how they are expressing themselves.

If you are having suicidal thoughts

If you live in the US and are having suicidal thoughts, call the National Suicide Prevention Lifeline at 800-273-8255 (800-273-TALK) for free and confidential support. It’s open 24 hours a day, seven days a week. For crisis support in Spanish, call 888-628-9454.

TrevorLifeline, a suicide prevention counseling service for the LGBTQ community, can be reached at 866-488-7386.

Befrienders Worldwide connects users to the nearest emotional support center for the part of the world they live in.

Crisis Text Line, which Biden mentioned, is an international service that provides a live, trained crisis counselor via a simple text for help. The first few responses will be automated until they get a counselor on the line — which typically takes less than five minutes.

If you are in the US or Canada, text 741741. If you are in the UK, text 85258 and those in Ireland can text 50808. The National Health Service also lists a variety of resources on its website.

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