Dustin Pedroia’s two-run double capped a seven-run sixth inning Thursday night that sent the Boston Red Sox to their fourth straight win, 9-4 over the Houston Astros.

Pedroia finished with three hits, Daniel Nava had two doubles and David Ortiz added two singles as the Red Sox improved to 8-0 at Fenway Park against the Astros.

 Matt Dominguez hit a two-run homer for Houston, which opened a 10-game road trip with its fourth loss in five games.

Allen Webster (3-1) gave up four runs — three earned — and five hits in six innings for Boston.

Trailing 4-1, the Red Sox chased starter Scott Feldman (6-9) during their biggest inning of the season.

Pedroia’s ground-rule double bounced off the chalk on the right-field line and caromed into the stands. Ortiz, Mike Napoli and Will Middlebrooks each had an RBI single before Jackie Bradley Jr. drew a bases-loaded walk from reliever Darin Downs that pushed Boston ahead 5-4.

Christian Vazquez had a sacrifice fly before Pedroia’s double. Brock Holt opened the inning with a hustle double and drew a walk as the Red Sox sent 12 batters to the plate.

Feldman was charged with seven runs and nine hits in 5 1-3 innings.

The Astros scored single runs in the second and third before Dominguez’s homer made it 4-0 in the fourth. Dominguez homered into the Green Monster seats after Jon Singleton’s leadoff walk.

Boston sliced it to 4-1 when Pedroia scored on Yoenis Cespedes’ double-play grounder.

TRAINER’S ROOM

Astros: OF Alex Presley won’t play in games and will only get treatment for a couple of days because he had some discomfort during his minor league rehabilitation assignment at Tri-City.

Red Sox: Cespedes was back in the lineup after coming out of Wednesday’s game with a bruised right hand. Manager John Farrell said outfielder Allen Craig, on the 15-day disabled list with a sprained left foot, will take batting practice the next few days before being sent on a rehab assignment.

UP NEXT

LHP Dallas Keuchel (10-8, 3.07 ERA) pitches Friday for the Astros after losing his last start, giving up five runs in six innings at home against Texas. It was his worst start in more than a month.

Red Sox RHP Clay Buchholz (5-7, 5.98) looks for his second strong start against Houston this season. He struck out 12 in a complete-game victory at Minute Maid Park on July 13.

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